Central defenders Winfield and Johnson missed the FA Cup defeat at home to Hereford in midweek with hamstring and knee injuries respectively and will face late fitness tests before travelling to Sincil Bank.
Alan Bennett and Chris Westwood formed a partnership at the back on Tuesday and could be called upon again as Wanderers look for a return to winning ways.
Veteran winger Gareth Ainsworth returns to Sincil Bank for the first time since 1997, having achieved cult status during his time there.
The 37-year-old scored 37 goals in 83 league starts for the Imps and will start against his former club.
Striker Jon-Paul Pittman remains a long-term absentee as he continues his recovery from a ruptured knee tendon which has kept him out since September.
Source: PA
Source: PA