Luton manager Mike Newell has had to endure eleven away FA cup ties from thirteen, whilst in charge at the club. The Hatters’ recent record in the competition hasn’t been particularly impressive as a result.
The Hatters also headed out of this season’s Carling Cup at League Two opponents Boston United back in September.
"It will be another tough match," said Newell.
The League One leaders have also won each of the seven previous meetings with Wycombe at the Causeway Stadium.