Winfield was dismissed during an ugly late brawl at Macclesfield on Saturday which saw every outfield Wycombe player involved, as well as Silkmen duo Ricky Sappleton and Emile Sinclair sent off.
He begins a three-match suspension but manager Gary Waddock has some good news in defence.
Centre-back Chris Westwood is back in contention after a fortnight out with a groin injury while Alan Bennett can play after missing the win at Moss Rose through illness.
On-loan Watford defender Rob Kiernan came off at the weekend with a knee injury but is also passed fit and midfielder Matt Bloomfield is in the squad after his hamstring strain.
Left-back Andy Sandell is still sidelined with a knee injury that is expected to keep him out for a minimum of six weeks.
Source: PA
Source: PA