Millwall striker Steve Morison will miss the match after receiving his first call up by Wales.
Darren Carter is suspended following his red card against Bristol City and Jimmy Abdou remains out injured.
MATCH FACTS
Head-to-head
• Wycombe and Millwall have each won five of their 14 previous meetings, with four draws.
• Wycombe did the double over the Lions in League One last season.
• They have never met in the League Cup, and Wycombe won on the only occasion they have clashed in a cup competition, progressing to the third round of the FA Cup in 2000 after a replay.
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Wycombe
• Wycombe have not managed to win a single match in the League Cup since their club record run in 2006/07 when they made the last four.
• The Chairboys have lost three of their last four League Cup matches by 4-0 margins, including the last two.
• This is Gary Waddock's first League Cup tie as manager of Wycombe.
Millwall
• Millwall's only League Cup victory in three years was a 4-0 win over Bournemouth at the New Den at this same stage last season, when Neil Harris bagged a hat-trick.
• The Lions, who are three-time quarter-finalists, need to score twice to bring their total of League Cup goals to 200.
Source: BBC Sport
Source: BBC Sport