The pace of Bristol City's Christian Roberts and Scott Murray as much as their second-half goals undid Wycombe.
Mickey Bell's scorching volley against his old club set up an exciting City win.
The former Wycombe wing-back hit a perfectly struck left foot shot from 20 yards to break the deadlock after 38 minutes after Craig Woodman's cross had been cleared.
City were unstoppable going forward in the second half and a thrilling break out of defence saw them increase their lead after 52 minutes.
Christian Roberts turned to beat two players and race away before timing his pass perfectly to Scott Murray who fired a low shot past Frank Talia.
Another fine move brought the third goal on 72 minutes.
Lee Peacock's pass found Murray who drew Talia before squaring for Roberts to shoot his first City goal into an unguarded net.
Wycombe had chances and Steve Phillips made excellent second-half saves to deny Keith Ryan and Paul McCarthy.
But at the other end the visiting defence was always stretched by the lively home attack, well supported by skipper Tommy Doherty and Aaron Brown in midfield.
Wycombe were unlucky not to take a 32nd minute lead when Sean Devine's shot on the turn hit the foot of the far post.
City had created most of the early chances, with Peacock and Murray going close in the opening ten minutes.
Murray's shot from inside the box was tipped over by Talia, while Peacock scooped the ball over from six yards.
City were without several key players and their young team, with defender Clayton Fortune making his first League start, looked fit and eager in the hot sunshine